Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

Ikaros family zinc finger 1 (IKZF1) is a haematopoietic transcription factor required for mammalian B-cell development. IKZF1 deficiency also reduces plasmacytoid dendritic cell (pDC) numbers in mice, but its effects on human DC development are unknown. Here we show that heterozygous mutation of IKZ...

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Publicado no:Nat Commun
Main Authors: Cytlak, Urszula, Resteu, Anastasia, Bogaert, Delfien, Kuehn, Hye Sun, Altmann, Thomas, Gennery, Andrew, Jackson, Graham, Kumanovics, Attila, Voelkerding, Karl V., Prader, Seraina, Dullaers, Melissa, Reichenbach, Janine, Hill, Harry, Haerynck, Filomeen, Rosenzweig, Sergio D., Collin, Matthew, Bigley, Venetia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869589/
https://ncbi.nlm.nih.gov/pubmed/29588478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02977-8
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