Ikaros family zinc finger 1 regulates dendritic cell development and function in humans

Ikaros family zinc finger 1 (IKZF1) is a haematopoietic transcription factor required for mammalian B-cell development. IKZF1 deficiency also reduces plasmacytoid dendritic cell (pDC) numbers in mice, but its effects on human DC development are unknown. Here we show that heterozygous mutation of IKZ...

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Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Cytlak, Urszula, Resteu, Anastasia, Bogaert, Delfien, Kuehn, Hye Sun, Altmann, Thomas, Gennery, Andrew, Jackson, Graham, Kumanovics, Attila, Voelkerding, Karl V., Prader, Seraina, Dullaers, Melissa, Reichenbach, Janine, Hill, Harry, Haerynck, Filomeen, Rosenzweig, Sergio D., Collin, Matthew, Bigley, Venetia
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869589/
https://ncbi.nlm.nih.gov/pubmed/29588478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02977-8
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