Endopeptidase PepO Regulates the SpeB Cysteine Protease and Is Essential for the Virulence of Invasive M1T1 Streptococcus pyogenes

Streptococcus pyogenes (group A Streptococcus [GAS]) causes a wide range of human infections. The pathogenesis of GAS infections is dependent on the temporal expression of numerous secreted and surface-associated virulence factors that interact with host proteins. Streptococcal pyrogenic exotoxin B...

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Veröffentlicht in:J Bacteriol
Hauptverfasser: Brouwer, Stephan, Cork, Amanda J., Ong, Cheryl-Lynn Y., Barnett, Timothy C., West, Nicholas P., McIver, Kevin S., Walker, Mark J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869480/
https://ncbi.nlm.nih.gov/pubmed/29378883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00654-17
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