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An irreversible inhibitor to probe the role of Streptococcus pyogenes cysteine protease SpeB in evasion of host complement defenses

Members of the CA class of cysteine proteases have multifaceted roles in physiology and virulence for many bacteria. Streptococcal pyrogenic exotoxin B (SpeB) is secreted by Streptococcus pyogenes and implicated in the pathogenesis of the bacterium through degradation of key human immune effector pr...

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Detaylı Bibliyografya
Yayımlandı:ACS Chem Biol
Asıl Yazarlar: Woehl, Jordan L., Kitamura, Seiya, Dillon, Nicholas, Han, Zhen, Edgar, Landon J., Nizet, Victor, Wolan, Dennis W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755099/
https://ncbi.nlm.nih.gov/pubmed/32662975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00191
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