Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated

In chronic kidney disease (CKD) patients, accumulation of uremic toxins is associated with cardiovascular risk and mortality. One of the hallmarks of kidney disease-related cardiovascular disease is intravascular macrophage inflammation, but the mechanism of the reaction with these toxins is not com...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Wakamatsu, Takuya, Yamamoto, Suguru, Ito, Toru, Sato, Yoko, Matsuo, Koji, Takahashi, Yoshimitsu, Kaneko, Yoshikatsu, Goto, Shin, Kazama, Junichiro James, Gejyo, Fumitake, Narita, Ichiei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869412/
https://ncbi.nlm.nih.gov/pubmed/29543732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10030124
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