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Indoxyl sulfate impairs angiogenesis via chronic aryl hydrocarbon receptor activation

Chronic kidney disease (CKD) is associated with a substantial increased risk of cardiovascular disease. There is growing evidence that uremic metabolites, which accumulate in the blood with CKD, have detrimental impacts on endothelial cell health and function. However, the molecular mechanisms by wh...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Salyers, Zachary R., Coleman, Madeline, Balestrieri, Nicholas P., Ryan, Terence E.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948007/
https://ncbi.nlm.nih.gov/pubmed/33406025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00262.2020
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