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Indoxyl sulfate impairs angiogenesis via chronic aryl hydrocarbon receptor activation

Chronic kidney disease (CKD) is associated with a substantial increased risk of cardiovascular disease. There is growing evidence that uremic metabolites, which accumulate in the blood with CKD, have detrimental impacts on endothelial cell health and function. However, the molecular mechanisms by wh...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Cell Physiol
Hoofdauteurs: Salyers, Zachary R., Coleman, Madeline, Balestrieri, Nicholas P., Ryan, Terence E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7948007/
https://ncbi.nlm.nih.gov/pubmed/33406025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00262.2020
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