Increased Proinflammatory Cytokine Production and Decreased Cholesterol Efflux Due to Downregulation of ABCG1 in Macrophages Exposed to Indoxyl Sulfate

One of the possible causes of enhanced atherosclerosis in patients with chronic kidney disease (CKD) is the accumulation of uremic toxins. Since macrophage foam cell formation is a hallmark of atherosclerosis, we examined the direct effect of indoxyl sulfate (IS), a representative uremic toxin, on m...

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Detaylı Bibliyografya
Yayımlandı:Toxins (Basel)
Asıl Yazarlar: Matsuo, Koji, Yamamoto, Suguru, Wakamatsu, Takuya, Takahashi, Yoshimitsu, Kawamura, Kazuko, Kaneko, Yoshikatsu, Goto, Shin, Kazama, Junichiro J., Narita, Ichiei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549743/
https://ncbi.nlm.nih.gov/pubmed/26287243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7083155
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