Increased Proinflammatory Cytokine Production and Decreased Cholesterol Efflux Due to Downregulation of ABCG1 in Macrophages Exposed to Indoxyl Sulfate

One of the possible causes of enhanced atherosclerosis in patients with chronic kidney disease (CKD) is the accumulation of uremic toxins. Since macrophage foam cell formation is a hallmark of atherosclerosis, we examined the direct effect of indoxyl sulfate (IS), a representative uremic toxin, on m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Toxins (Basel)
Egile Nagusiak: Matsuo, Koji, Yamamoto, Suguru, Wakamatsu, Takuya, Takahashi, Yoshimitsu, Kawamura, Kazuko, Kaneko, Yoshikatsu, Goto, Shin, Kazama, Junichiro J., Narita, Ichiei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549743/
https://ncbi.nlm.nih.gov/pubmed/26287243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7083155
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