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Structure-based drug design: aiming for a perfect fit

Knowledge of the three-dimensional structure of therapeutically relevant targets has informed drug discovery since the first protein structures were determined using X-ray crystallography in the 1950s and 1960s. In this editorial we provide a brief overview of the powerful impact of structure-based...

詳細記述

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書誌詳細
出版年:Essays Biochem
主要な著者: van Montfort, Rob L.M., Workman, Paul
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869280/
https://ncbi.nlm.nih.gov/pubmed/29118091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170052
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