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Structure-based drug design: aiming for a perfect fit
Knowledge of the three-dimensional structure of therapeutically relevant targets has informed drug discovery since the first protein structures were determined using X-ray crystallography in the 1950s and 1960s. In this editorial we provide a brief overview of the powerful impact of structure-based...
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| Publicado no: | Essays Biochem |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869280/ https://ncbi.nlm.nih.gov/pubmed/29118091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/EBC20170052 |
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