T cell RANKL/OPG imbalance is associated with HIV-induced bone loss in patients with higher CD4(+) T cell counts

OBJECTIVE: Higher incidence of osteopenia and osteoporosis underlie increased rates of fragility fracture in HIV infection. B cells are a major source of Osteoprotegerin (OPG), an inhibitor of the key osteoclastogenic cytokine Receptor Activator of Nuclear Factor-κB Ligand (RANKL). We previously sho...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:AIDS
Hauptverfasser: TITANJI, Kehmia, VUNNAVA, Aswani, FOSTER, Antonina, SHETH, Anandi N., LENNOX, Jeffrey L., KNEZEVIC, Andrea, SHENVI, Neeta, EASLEY, Kirk A., OFOTOKUN, Ighovwerha, WEITZMANN, M. Neale
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5869175/
https://ncbi.nlm.nih.gov/pubmed/29424771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001764
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge