Antiretroviral Therapy Induces a Rapid Increase in Bone Resorption that is Positively Associated with the Magnitude of Immune Reconstitution in HIV Infection

OBJECTIVE: Antiretroviral therapy (ART) paradoxically intensifies bone loss in the setting of HIV-infection. Although the extent of bone loss varies, it occurs with virtually all ART types, suggesting a common pathway that may be aligned with HIV disease reversal. Using an animal model of immunodefi...

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Detalhes bibliográficos
Publicado no:AIDS
Main Authors: Ofotokun, Ighovwerha, Titanji, Kehmia, Vunnava, Aswani, Roser-Page, Susanne, Vikulina, Tatyana, Villinger, Francois, Rogers, Kenneth, Sheth, Anandi N, Lahiri, Cecile Delille, Lennox, Jeffrey L., Weitzmann, M. Neale
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712729/
https://ncbi.nlm.nih.gov/pubmed/26760232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000918
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