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T cell RANKL/OPG imbalance is associated with HIV-induced bone loss in patients with higher CD4(+) T cell counts
OBJECTIVE: Higher incidence of osteopenia and osteoporosis underlie increased rates of fragility fracture in HIV infection. B cells are a major source of Osteoprotegerin (OPG), an inhibitor of the key osteoclastogenic cytokine Receptor Activator of Nuclear Factor-κB Ligand (RANKL). We previously sho...
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| Publicado no: | AIDS |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5869175/ https://ncbi.nlm.nih.gov/pubmed/29424771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000001764 |
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