Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo

INTRODUCTION: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted ligands, such as trastuzumab (TMAB), have high molecular weight, limiting their application for targeting. In this study, we prepared Fab’ (a...

Full description

Saved in:
Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Duan, Dongyu, Wang, Aiping, Ni, Ling, Zhang, Liping, Yan, Xiuju, Jiang, Ying, Mu, Hongjie, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2018
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://ncbi.nlm.nih.gov/pubmed/29606874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S153795
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items