Development of (6R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis

[Image: see text] Discovery of the potent antileishmanial effects of antitubercular 6-nitro-2,3-dihydroimidazo[2,1-b][1,3]oxazoles and 7-substituted 2-nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines stimulated the examination of further scaffolds (e.g., 2-nitro-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]oxaz...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Med Chem
Hoofdauteurs: Thompson, Andrew M., O’Connor, Patrick D., Marshall, Andrew J., Blaser, Adrian, Yardley, Vanessa, Maes, Louis, Gupta, Suman, Launay, Delphine, Braillard, Stephanie, Chatelain, Eric, Wan, Baojie, Franzblau, Scott G., Ma, Zhenkun, Cooper, Christopher B., Denny, William A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2018
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867678/
https://ncbi.nlm.nih.gov/pubmed/29461823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b01581
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items