Microvascular insulin resistance in skeletal muscle and brain occurs early in the development of juvenile obesity in pigs

Impaired microvascular insulin signaling may develop before overt indices of microvascular endothelial dysfunction and represent an early pathological feature of adolescent obesity. Using a translational porcine model of juvenile obesity, we tested the hypotheses that in the early stages of obesity...

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Gepubliceerd in:Am J Physiol Regul Integr Comp Physiol
Hoofdauteurs: Olver, T. Dylan, Grunewald, Zachary I., Jurrissen, Thomas J., MacPherson, Rebecca E. K., LeBlanc, Paul J., Schnurbusch, Teagan R., Czajkowski, Alana M., Laughlin, M. Harold, Rector, R. Scott, Bender, Shawn B., Walters, Eric M., Emter, Craig A., Padilla, Jaume
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2018
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867673/
https://ncbi.nlm.nih.gov/pubmed/29141949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00213.2017
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