Microvascular insulin resistance in skeletal muscle and brain occurs early in the development of juvenile obesity in pigs

Impaired microvascular insulin signaling may develop before overt indices of microvascular endothelial dysfunction and represent an early pathological feature of adolescent obesity. Using a translational porcine model of juvenile obesity, we tested the hypotheses that in the early stages of obesity...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Olver, T. Dylan, Grunewald, Zachary I., Jurrissen, Thomas J., MacPherson, Rebecca E. K., LeBlanc, Paul J., Schnurbusch, Teagan R., Czajkowski, Alana M., Laughlin, M. Harold, Rector, R. Scott, Bender, Shawn B., Walters, Eric M., Emter, Craig A., Padilla, Jaume
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867673/
https://ncbi.nlm.nih.gov/pubmed/29141949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00213.2017
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