Microvascular insulin resistance in skeletal muscle and brain occurs early in the development of juvenile obesity in pigs

Impaired microvascular insulin signaling may develop before overt indices of microvascular endothelial dysfunction and represent an early pathological feature of adolescent obesity. Using a translational porcine model of juvenile obesity, we tested the hypotheses that in the early stages of obesity...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Olver, T. Dylan, Grunewald, Zachary I., Jurrissen, Thomas J., MacPherson, Rebecca E. K., LeBlanc, Paul J., Schnurbusch, Teagan R., Czajkowski, Alana M., Laughlin, M. Harold, Rector, R. Scott, Bender, Shawn B., Walters, Eric M., Emter, Craig A., Padilla, Jaume
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867673/
https://ncbi.nlm.nih.gov/pubmed/29141949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00213.2017
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