Llwytho...

High complement levels in astrocyte-derived exosomes of Alzheimer's disease

OBJECTIVE: Astrocytes fulfill neuronal trophic roles normally, but are transformed in Alzheimer's disease (AD) into A1-type reactive astrocytes that may destroy neurons through unknown mechanisms. METHODS: To investigate astrocyte inflammatory mechanisms, astrocyte-derived exosomes (ADEs) were...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ann Neurol
Prif Awduron: Goetzl, Edward J., Schwartz, Janice B., Abner, Erin L., Jicha, Gregory A., Kapogiannis, Dimitrios
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867263/
https://ncbi.nlm.nih.gov/pubmed/29406582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25172
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