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High complement levels in astrocyte-derived exosomes of Alzheimer's disease
OBJECTIVE: Astrocytes fulfill neuronal trophic roles normally, but are transformed in Alzheimer's disease (AD) into A1-type reactive astrocytes that may destroy neurons through unknown mechanisms. METHODS: To investigate astrocyte inflammatory mechanisms, astrocyte-derived exosomes (ADEs) were...
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| Publicado no: | Ann Neurol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5867263/ https://ncbi.nlm.nih.gov/pubmed/29406582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25172 |
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