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Altered lysosomal proteins in neural-derived plasma exosomes in preclinical Alzheimer disease
OBJECTIVE: Diverse autolysosomal proteins were quantified in neurally derived blood exosomes from patients with Alzheimer disease (AD) and controls to investigate disordered neuronal autophagy. METHODS: Blood exosomes obtained once from patients with AD (n = 26) or frontotemporal dementia (n = 16),...
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Publicado no: | Neurology |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Lippincott Williams & Wilkins
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501943/ https://ncbi.nlm.nih.gov/pubmed/26062630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001702 |
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