Identification of pre-clinical Alzheimer’s disease by a profile of pathogenic proteins in neurally-derived blood exosomes: a case-control study

BACKGROUND: Proteins pathogenic in Alzheimer’s disease (AD) were extracted from neurally-derived blood exosomes and quantified to develop biomarkers for staging of sporadic AD. METHODS: Blood exosomes obtained at one time-point from patients with AD (n=57) or frontotemporal dementia (FTD) (n=16), an...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Fiandaca, Massimo S., Kapogiannis, Dimitrios, Mapstone, Mark, Boxer, Adam, Eitan, Erez, Schwartz, Janice B., Abner, Erin L., Petersen, Ronald C., Federoff, Howard J., Miller, Bruce L., Goetzl, Edward J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329112/
https://ncbi.nlm.nih.gov/pubmed/25130657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2014.06.008
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