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Population exposure–safety analysis of cediranib for Phase I and II studies in patients with cancer

AIMS: A multistudy analysis of cediranib, a potent, selective inhibitor of all three vascular endothelial growth factor receptors (VEGFR‐1, ‐2 and ‐3), was conducted to establish population exposure–safety models for the relationship of cediranib exposure to the safety endpoints, diastolic and systo...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Clin Pharmacol
Päätekijät: Al‐Huniti, Nidal, Petersson, Klas, Tang, Weifeng, Masson, Eric, Li, Jianguo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867133/
https://ncbi.nlm.nih.gov/pubmed/29274100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13495
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