Physician Awareness of Immune Responses to Polyethylene Glycol‐Drug Conjugates

Antibodies against polyethylene glycol (PEG) can critically jeopardize the efficacy and safety of PEGylated therapeutics. For some PEG‐drugs, a sizeable fraction of patients develop anti‐PEG antibodies (APA), leading to reduced efficacy and potential adverse events. We surveyed physicians from sever...

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Vydáno v:Clin Transl Sci
Hlavní autoři: McSweeney, Morgan D., Versfeld, Zina C., Carpenter, Delesha M., Lai, Samuel K.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866984/
https://ncbi.nlm.nih.gov/pubmed/29383836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12537
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