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Pretargeted delivery of PEG-coated drug carriers to breast tumors using multivalent, bispecific antibody against polyethylene glycol and HER2

Pretargeting is an increasingly explored strategy to improve nanoparticle targeting, in which pretargeting molecules that bind both selected epitopes on target cells and nanocarriers are first administered, followed by the drug-loaded nanocarriers. Bispecific antibodies (bsAb) represent a promising...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Parker, Christina L., McSweeney, Morgan D., Lucas, Andrew T., Jacobs, Timothy M., Wadsworth, Daniel, Zamboni, William C., Lai, Samuel K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7224238/
https://ncbi.nlm.nih.gov/pubmed/31394261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102076
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