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Layered dynamic regulation for improving metabolic pathway productivity in Escherichia coli

Microbial production of value-added chemicals from biomass is a sustainable alternative to chemical synthesis. To improve product titer, yield, and selectivity, the pathways engineered into microbes must be optimized. One strategy for optimization is dynamic pathway regulation, which modulates expre...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Doong, Stephanie J., Gupta, Apoorv, Prather, Kristala L. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866568/
https://ncbi.nlm.nih.gov/pubmed/29507236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716920115
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