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Dynamic regulation of metabolic flux in engineered bacteria using a pathway-independent quorum-sensing circuit

Metabolic engineering of microorganisms to produce desirable products on an industrial scale can result in unbalanced cellular metabolic networks that reduce productivity and yield. Metabolic fluxes can be rebalanced using dynamic pathway regulation, but few broadly applicable tools are available to...

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Bibliographic Details
Published in:Nat Biotechnol
Main Authors: Gupta, Apoorv, Brockman Reizman, Irene M., Reisch, Christopher R., Prather, Kristala L. J.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340623/
https://ncbi.nlm.nih.gov/pubmed/28191902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3796
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