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Metabolic Engineering of Escherichia coli for Enhanced Production of (R)- and (S)-3-Hydroxybutyrate

Synthetic metabolic pathways have been constructed for the production of enantiopure (R)- and (S)-3-hydroxybutyrate (3HB) from glucose in recombinant Escherichia coli strains. To promote maximal activity, we profiled three thiolase homologs (BktB, Thl, and PhaA) and two coenzyme A (CoA) removal mech...

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Bibliografski detalji
Glavni autori: Tseng, Hsien-Chung, Martin, Collin H., Nielsen, David R., Prather, Kristala L. Jones
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681625/
https://ncbi.nlm.nih.gov/pubmed/19304817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02667-08
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