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Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis

OBJECTIVES: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles. At the cellular and molecular level, osteoarthritis (OA) is cha...

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Pubblicato in:J Orthop Translat
Autori principali: Wang, Cuicui, Silverman, Richard M., Shen, Jie, O'Keefe, Regis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Chinese Speaking Orthopaedic Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866480/
https://ncbi.nlm.nih.gov/pubmed/29662780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jot.2017.12.004
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