Distinct metabolic programs induced by TGF-β1 and BMP2 in human articular chondrocytes with osteoarthritis

OBJECTIVES: Cellular energy metabolism is important for the function of all tissues, including cartilage. Recent studies indicate that superficial and deep subpopulations of articular chondrocytes (ACs) have distinct metabolic profiles. At the cellular and molecular level, osteoarthritis (OA) is cha...

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Veröffentlicht in:J Orthop Translat
Hauptverfasser: Wang, Cuicui, Silverman, Richard M., Shen, Jie, O'Keefe, Regis J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Chinese Speaking Orthopaedic Society 2018
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866480/
https://ncbi.nlm.nih.gov/pubmed/29662780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jot.2017.12.004
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