IL-8 mediates idiopathic pulmonary fibrosis mesenchymal progenitor cell fibrogenicity

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease, but the mechanisms driving progression remain incompletely defined. We previously reported that the IPF lung harbors fibrogenic mesenchymal progenitor cells (MPCs), which serve as a cell of origin for IPF fibroblasts. Prolif...

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Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Yang, Libang, Herrera, Jeremy, Gilbertsen, Adam, Xia, Hong, Smith, Karen, Benyumov, Alexey, Bitterman, Peter B., Henke, Craig A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2018
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866425/
https://ncbi.nlm.nih.gov/pubmed/28860143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00200.2017
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