TRAF3IP2 mediates high glucose-induced endothelin-1 production as well as endothelin-1-induced inflammation in endothelial cells

Hyperglycemia-induced production of endothelin (ET)-1 is a hallmark of endothelial dysfunction in diabetes. Although the detrimental vascular effects of increased ET-1 are well known, the molecular mechanisms regulating endothelial synthesis of ET-1 in the setting of diabetes remain largely unidenti...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Padilla, Jaume, Carpenter, Andrea J., Das, Nitin A., Kandikattu, Hemanth Kumar, López-Ongil, Susana, Martinez-Lemus, Luis A., Siebenlist, Ulrich, DeMarco, Vincent G., Chandrasekar, Bysani
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866390/
https://ncbi.nlm.nih.gov/pubmed/28971844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00478.2017
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