Genome‐Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β‐Blockers

BACKGROUND: For many indications, the negative chronotropic effect of β‐blockers is important to their efficacy, yet the heart rate (HR) response to β‐blockers varies. Herein, we sought to use a genome‐wide association approach to identify novel single nucleotide polymorphisms (SNPs) associated with...

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Detaylı Bibliyografya
Yayımlandı:J Am Heart Assoc
Asıl Yazarlar: Shahin, Mohamed H., Conrado, Daniela J., Gonzalez, Daniel, Gong, Yan, Lobmeyer, Maximilian T., Beitelshees, Amber L., Boerwinkle, Eric, Gums, John G., Chapman, Arlene, Turner, Stephen T., Cooper‐DeHoff, Rhonda M., Johnson, Julie A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866313/
https://ncbi.nlm.nih.gov/pubmed/29478026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006463
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