Genome‐Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β‐Blockers

BACKGROUND: For many indications, the negative chronotropic effect of β‐blockers is important to their efficacy, yet the heart rate (HR) response to β‐blockers varies. Herein, we sought to use a genome‐wide association approach to identify novel single nucleotide polymorphisms (SNPs) associated with...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Shahin, Mohamed H., Conrado, Daniela J., Gonzalez, Daniel, Gong, Yan, Lobmeyer, Maximilian T., Beitelshees, Amber L., Boerwinkle, Eric, Gums, John G., Chapman, Arlene, Turner, Stephen T., Cooper‐DeHoff, Rhonda M., Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866313/
https://ncbi.nlm.nih.gov/pubmed/29478026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.006463
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