POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express leptin receptors (LEPRs). However, previous studies have...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Caron, Alexandre, Dungan Lemko, Heather M, Castorena, Carlos M, Fujikawa, Teppei, Lee, Syann, Lord, Caleb C, Ahmed, Newaz, Lee, Charlotte E, Holland, William L, Liu, Chen, Elmquist, Joel K
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Human Biology and Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866097/
https://ncbi.nlm.nih.gov/pubmed/29528284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33710
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