POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express leptin receptors (LEPRs). However, previous studies have...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Caron, Alexandre, Dungan Lemko, Heather M, Castorena, Carlos M, Fujikawa, Teppei, Lee, Syann, Lord, Caleb C, Ahmed, Newaz, Lee, Charlotte E, Holland, William L, Liu, Chen, Elmquist, Joel K
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Human Biology and Medicine
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866097/
https://ncbi.nlm.nih.gov/pubmed/29528284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33710
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