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POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels
Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express leptin receptors (LEPRs). However, previous studies have...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5866097/ https://ncbi.nlm.nih.gov/pubmed/29528284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33710 |
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