POMC neurons expressing leptin receptors coordinate metabolic responses to fasting via suppression of leptin levels

Leptin is critical for energy balance, glucose homeostasis, and for metabolic and neuroendocrine adaptations to starvation. A prevalent model predicts that leptin’s actions are mediated through pro-opiomelanocortin (POMC) neurons that express leptin receptors (LEPRs). However, previous studies have...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Caron, Alexandre, Dungan Lemko, Heather M, Castorena, Carlos M, Fujikawa, Teppei, Lee, Syann, Lord, Caleb C, Ahmed, Newaz, Lee, Charlotte E, Holland, William L, Liu, Chen, Elmquist, Joel K
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5866097/
https://ncbi.nlm.nih.gov/pubmed/29528284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.33710
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