Galectin-3 sensitized melanoma cell lines to vemurafenib (PLX4032) induced cell death through prevention of autophagy

Melanoma is a current worldwide problem, as its incidence is increasing. In the last years, several studies have shown that melanoma cells display high levels of autophagy, a self-degradative process that can promote survival leading to drug resistance. Consequently, autophagy regulation represents...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Bustos, Silvina Odete, da Silva Pereira, Gustavo José, de Freitas Saito, Renata, Gil, Cristiane Damas, Zanatta, Daniela Bertolli, Smaili, Soraya Soubhi, Chammas, Roger
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865690/
https://ncbi.nlm.nih.gov/pubmed/29581864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24516
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