Chargement en cours...
Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10
Toll-like receptor (TLR)-10 remains an orphan receptor without well-characterized ligands or functions. Here, we reveal that TLR10 is predominantly localized to endosomes and binds dsRNA in vitro at endosomal pH, suggesting that dsRNA is a ligand of TLR10. Recognition of dsRNA by TLR10 activates rec...
Enregistré dans:
| Publié dans: | Front Immunol |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2018
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865411/ https://ncbi.nlm.nih.gov/pubmed/29616030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00516 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|