Llwytho...
Recognition of Double-Stranded RNA and Regulation of Interferon Pathway by Toll-Like Receptor 10
Toll-like receptor (TLR)-10 remains an orphan receptor without well-characterized ligands or functions. Here, we reveal that TLR10 is predominantly localized to endosomes and binds dsRNA in vitro at endosomal pH, suggesting that dsRNA is a ligand of TLR10. Recognition of dsRNA by TLR10 activates rec...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Front Immunol |
|---|---|
| Prif Awduron: | , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Frontiers Media S.A.
2018
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5865411/ https://ncbi.nlm.nih.gov/pubmed/29616030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00516 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|