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Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism

Small molecular inhibitors and passive immunization against Ebola virus disease (EVD) have been tested in animal models, including rodents and non-human primates, as well as in clinical trials. Nevertheless, there is currently no Food and Drug Administration (FDA)-approved therapy, and alternative s...

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Dettagli Bibliografici
Pubblicato in:Emerg Microbes Infect
Autori principali: Seesuay, Watee, Jittavisutthikul, Surasak, Sae-lim, Nawannaporn, Sookrung, Nitat, Sakolvaree, Yuwaporn, Chaicumpa, Wanpen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864874/
https://ncbi.nlm.nih.gov/pubmed/29568066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0031-3
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