PHA-4/FoxA senses nucleolar stress to regulate lipid accumulation in Caenorhabditis elegans

The primary function of the nucleolus is ribosome biogenesis, which is an extremely energetically expensive process. Failures in ribosome biogenesis cause nucleolar stress with an altered energy status. However, little is known about the underlying mechanism linking nucleolar stress to energy metabo...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Wu, Jieyu, Jiang, Xue, Li, Yamei, Zhu, Tingting, Zhang, Jingjing, Zhang, Zhiguo, Zhang, Linqiang, Zhang, Yuru, Wang, Yanli, Zou, Xiaoju, Liang, Bin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864837/
https://ncbi.nlm.nih.gov/pubmed/29567958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03531-2
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