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PHA-4/FoxA cooperates with TAM-1/TRIM to regulate cell fate restriction in the C. elegans foregut

A key question in development is how pluripotent progenitors are progressively restricted to acquire specific cell fates. Here we investigate how embryonic blastomeres in C. elegans develop into foregut (pharynx) cells in response to the selector gene PHA-4/FoxA. When pha-4 is removed from pharyngea...

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Detalhes bibliográficos
Main Authors: Kiefer, Julie C., Smith, Pliny A., Mango, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1855296/
https://ncbi.nlm.nih.gov/pubmed/17250823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2006.11.042
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