PHA-4/FoxA senses nucleolar stress to regulate lipid accumulation in Caenorhabditis elegans

The primary function of the nucleolus is ribosome biogenesis, which is an extremely energetically expensive process. Failures in ribosome biogenesis cause nucleolar stress with an altered energy status. However, little is known about the underlying mechanism linking nucleolar stress to energy metabo...

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Udgivet i:Nat Commun
Main Authors: Wu, Jieyu, Jiang, Xue, Li, Yamei, Zhu, Tingting, Zhang, Jingjing, Zhang, Zhiguo, Zhang, Linqiang, Zhang, Yuru, Wang, Yanli, Zou, Xiaoju, Liang, Bin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864837/
https://ncbi.nlm.nih.gov/pubmed/29567958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03531-2
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