Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1

PKD2L1, also termed TRPP3 from the TRPP subfamily (polycystic TRP channels), is involved in the sour sensation and other pH-dependent processes. PKD2L1 is believed to be a nonselective cation channel that can be regulated by voltage, protons, and calcium. Despite its considerable importance, the mol...

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Publicat a:Nat Commun
Autors principals: Su, Qiang, Hu, Feizhuo, Liu, Yuxia, Ge, Xiaofei, Mei, Changlin, Yu, Shengqiang, Shen, Aiwen, Zhou, Qiang, Yan, Chuangye, Lei, Jianlin, Zhang, Yanqing, Liu, Xiaodong, Wang, Tingliang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864754/
https://ncbi.nlm.nih.gov/pubmed/29567962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03606-0
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