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Identification of p38 MAPK as a novel therapeutic target for Friedreich’s ataxia
Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC) assembly. There are no proven effective treatments for FRDA. We previously scr...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864720/ https://ncbi.nlm.nih.gov/pubmed/29568068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23168-x |
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