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Insights into the role of oxidative stress in the pathology of Friedreich ataxia using peroxidation resistant polyunsaturated fatty acids

Friedreich ataxia is an autosomal recessive, inherited neuro- and cardio-degenerative disorder characterized by progressive ataxia of all four limbs, dysarthria, areflexia, sensory loss, skeletal deformities, and hypertrophic cardiomyopathy. Most disease alleles have a trinucleotide repeat expansion...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Cotticelli, M. Grazia, Crabbe, Andrew M., Wilson, Robert B., Shchepinov, Mikhail S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4802835/
https://ncbi.nlm.nih.gov/pubmed/25499576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.06.004
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