Pregnenolone-progesterone-allopregnanolone pathway as a potential therapeutic target in first-episode antipsychotic-naïve patients with schizophrenia

Neurosteroids are both endogenous and exogenous steroids that rapidly alter neuronal excitability through interactions with ligand-gated ion channels and other cell surface receptors. They are originated from cholesterol and have important implications for schizophrenia (SZ) pathophysiology and trea...

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Udgivet i:Psychoneuroendocrinology
Main Authors: Cai, HuaLin, Zhou, Xiang, Dougherty, George G., Reddy, Ravinder D., Haas, Gretchen L., Montrose, Debra M., Keshavan, Matcheri, Yao, Jeffrey K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864547/
https://ncbi.nlm.nih.gov/pubmed/29433072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2018.02.004
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