Homeostatic Imbalance of Purine Catabolism in First-Episode Neuroleptic-Naïve Patients with Schizophrenia

BACKGROUND: Purine catabolism may be an unappreciated, but important component of the homeostatic response of mitochondria to oxidant stress. Accumulating evidence suggests a pivotal role of oxidative stress in schizophrenia pathology. METHODOLOGY/PRINCIPAL FINDINGS: Using high-pressure liquid chrom...

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Detalhes bibliográficos
Main Authors: Yao, Jeffrey K., Dougherty, George G., Reddy, Ravinder D., Keshavan, Matcheri S., Montrose, Debra M., Matson, Wayne R., McEvoy, Joseph, Kaddurah-Daouk, Rima
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831068/
https://ncbi.nlm.nih.gov/pubmed/20209081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009508
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