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Associations between Purine Metabolites and Clinical Symptoms in Schizophrenia

BACKGROUND: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology of schizophrenia. METHODOLOGY/PRINCIPAL FINDI...

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Detalhes bibliográficos
Main Authors: Yao, Jeffrey K., Condray, Ruth, Dougherty, George G., Keshavan, Matcheri S., Montrose, Debra M., Matson, Wayne R., McEvoy, Joseph, Kaddurah-Daouk, Rima, Reddy, Ravinder D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419238/
https://ncbi.nlm.nih.gov/pubmed/22916123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042165
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