Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models

Colorectal cancer (CRC) is a highly heterogeneous disease both from a molecular and clinical perspective. Several distinct molecular entities, such as microsatellite instability (MSI), have been defined that make up biologically distinct subgroups with their own clinical course. Recent data indicate...

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Udgivet i:Cell Death Differ
Main Authors: Linnekamp, Janneke F., Hooff, Sander R. van, Prasetyanti, Pramudita R., Kandimalla, Raju, Buikhuisen, Joyce Y., Fessler, Evelyn, Ramesh, Prashanthi, Lee, Kelly A. S. T., Bochove, Grehor G. W., de Jong, Johan H., Cameron, Kate, Leersum, Ronald van, Rodermond, Hans M., Franitza, Marek, Nürnberg, Peter, Mangiapane, Laura R., Wang, Xin, Clevers, Hans, Vermeulen, Louis, Stassi, Giorgio, Medema, Jan Paul
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864202/
https://ncbi.nlm.nih.gov/pubmed/29305587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0011-5
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