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Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion
Cells undergoing Bax/Bak-mediated apoptosis exhibit signs of autophagy, but how it is activated and its significance is unknown. By directly activating Bax/Bak with BH3-only proteins or BH3 mimetic compounds, we demonstrate that mitochondrial damage correlated with a rapid increase in intracellular...
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| Vydáno v: | Cell Death Differ |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5864185/ https://ncbi.nlm.nih.gov/pubmed/29229994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-017-0017-z |
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