Testing therapeutics in cell-based assays: Factors that influence the apparent potency of drugs

Identifying effective antivirals for treating Ebola virus disease (EVD) and minimizing transmission of such disease is critical. A variety of cell-based assays have been developed for evaluating compounds for activity against Ebola virus. However, very few reports discuss the variable assay conditio...

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Veröffentlicht in:PLoS One
Hauptverfasser: Postnikova, Elena, Cong, Yu, DeWald, Lisa Evans, Dyall, Julie, Yu, Shuiqing, Hart, Brit J., Zhou, Huanying, Gross, Robin, Logue, James, Cai, Yingyun, Deiuliis, Nicole, Michelotti, Julia, Honko, Anna N., Bennett, Richard S., Holbrook, Michael R., Olinger, Gene G., Hensley, Lisa E., Jahrling, Peter B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5864066/
https://ncbi.nlm.nih.gov/pubmed/29566079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0194880
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